Which immunoglobulin causes allergic reactions as a result of release of histamine from mast cells?

Question

Quizplus · Accepted Answer

IgE is the immunoglobulin responsible for allergic reactions, as it binds to antigens on mast cells and triggers their degranulation, leading to the release of histamine and other inflammatory mediators. This can result in symptoms such as hives, itching, and swelling, as well as more severe reactions like anaphylaxis. IgA, IgD, and IgM do not play a significant role in allergic reactions.

Which Immunoglobulin Causes Allergic Reactions as a Result of Release