An individual visits a physician,who notes that the patient has splenomegaly,enlarged and orange-colored tonsils,and tingling feelings in the extremities,indicating peripheral neuropathy.Upon examination of the blood smear for a white blood cell differential,many foamy-appearing cells were noted.Normal triglyceride and total cholesterol values were noted; however,a marked decrease of HDL was also noted.What is the name of this disorder?

Question

Quizplus · Accepted Answer

The symptoms of splenomegaly, enlarged and orange-colored tonsils, and peripheral neuropathy are consistent with Tangier disease. The presence of foamy-appearing cells on the blood smear and a marked decrease of HDL are also characteristic of Tangier disease. Normal triglyceride and total cholesterol values rule out familial hypercholesterolemia and dysbetalipoproteinemia. Coronary heart disease is a broad term that does not specifically fit the symptoms and laboratory findings described.

An Individual Visits a Physician,who Notes That the Patient Has