The difference between traditional HDL cholesterol assays and the direct homogeneous assay is that:

Question

Quizplus · Accepted Answer

The direct homogeneous assay measures HDL cholesterol without physically separating it from the non-HDL fractions. It selectively measures HDL cholesterol, whereas traditional HDL assays require enzymatic measurement after non-HDL lipoprotein removal through processes such as precipitation or ultracentrifugation. Option B and C mention precipitation and ultracentrifugation, respectively, which are used in traditional assays, but not in direct homogeneous assays. Option D is not relevant to the comparison of HDL cholesterol assays.

The Difference Between Traditional HDL Cholesterol Assays and the Direct