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What Is the Mutational Basis of an "Elongation Hemoglobin

Question 10

Multiple Choice

What is the mutational basis of an "elongation hemoglobin?"


A) A gene deletion of the entire alpha2 globin gene
B) A reciprocal chromosomal translocation between chromosomes 16 and 14 of the alpha and beta globin chain genes
C) Many fixed mutations occurring along the genes encoding for alpha2 globin
D) A single base pair mutation or frameshift at either the 3' end of exon 3 or the 5' end of exon 1 of the alpha2 or beta globin chain

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