The Use of the Urea Breath Test for Detection of H.pylori

The use of the urea breath test for detection of H.pylori involves:

A) titration of bacterial free acid in breath with sodium hydroxide to a pH end point of 3.5 compared with a urea standard.
B) immunoassay measurement of deficiency of IgA-class transglutaminase in breath using tissue transglutaminase as an antigen.
C) bacterial hydrolysis of ingested labeled urea producing labeled bicarbonate,which is absorbed into the blood and exhaled as ¹⁴CO₂ or ¹³CO₂.
D) production of hydrogen by bacterial metabolism that is absorbed into the systemic circulation and exhaled in the breath as urea.