Explain how lithium works to decrease nerve conduction.
A) Lithium blocks the reuptake of norepinephrine and serotonin back into the neuronal nerve endings, resulting in increases in the level of neuronal activity, thereby alleviating the symptoms.
B) The body uses lithium as if it were sodium. Na+ is normally required for conduction of nerve impulses; Li+ interferes with the nerve conduction, resulting in a decrease in the excitability of nerve tissue.
C) Lithium acts directly to stimulate norepinephrine and dopamine receptors, which stimulate the release of norepinephrine and dopamine from the nerve endings, and it inhibits the reuptake of these neurotransmitters back into the nerve endings, alleviating the symptoms.
D) None of these are correct.
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