Select the Mechanism of Action of Topiramate (Topamax)

Select the mechanism of action of topiramate (Topamax) .

A) Topiramate interferes with the action of Na+ ions and the generation of high-frequency action potentials. The drug may also increase the inhibitory actions of gamma-aminobutyric acid.
B) Topiramate shortens the inactivation period of sodium ion (Na+) channels in the nerve membrane, leading to a reduction in the generation of high-frequency repetitive firing of action potentials from neurons involved in initiating seizures.
C) Topiramate reduces the T-type calcium currents in the thalamus, which reduces the occurrence of seizures.
D) Topiramate prolongs the inactivation period of potassium (K+) channels in the nerve membrane, leading to a reduction in the generation of high-frequency repetitive firing of action potentials from neurons involved in initiating seizures.