Which of the following is seen in the transaminase mechanism?
A)aldimine formed between pyridoxal and lysine residue
B)Schiff base
C)pyridoxamine phosphate that reacts only with an $\alpha$-ketoacid
D)a carbanion that is resonance stabilized as a quinonoid intermediate
E)all of the above

Question

Quizplus · Accepted Answer

All of the above are seen in the transaminase mechanism. The formation of an aldimine between pyridoxal and a lysine residue, the formation of a Schiff base intermediate, and the use of pyridoxamine phosphate as a coenzyme that reacts with only certain ketoacids are all part of the transaminase mechanism. Additionally, a carbanion intermediate is formed and stabilized by resonance as a quinonoid intermediate during the transamination reaction.

Which of the Following Is Seen in the Transaminase Mechanism α\alphaα

Which of the Following Is Seen in the Transaminase Mechanism $\alpha$