Why was the use of the sweat gland cDNA library critical in identifying the CF gene?
1)The CF gene is only expressed in epithelial cells of the lungs,pancreas,salivary glands,sweat glands,intestine,and reproductive tract
2)The CF gene is not expressed in any other tissue than sweat glands
3)The CF gene is not expressed in sweat glands
A) 1
B) 2
C) 3
D) 1 and 2
E) All of these

Question

Quizplus · Accepted Answer

The use of the sweat gland cDNA library was critical in identifying the CF gene because the CF gene is expressed in various tissues, including sweat glands. Therefore, the cDNA library derived from human sweat glands provided a rich source of genetic material, which was essential for identifying the CF gene. Option 2 and 3 are incorrect as they are directly contradictory to the fact that the CF gene is expressed in various tissues.

Why Was the Use of the Sweat Gland CDNA Library