When testing for the presence of the sickle cell anemia Hbb allele,a Southern blot exhibits two small bands for the Hbb? allele and one band for the Hbb allele.What do these results mean?
A) The subject is homozygous for the sickle cell allele
B) The subject is heterozygous
C) The subject is homozygous for the normal allele
D) The results are inconclusive and the test will need to be run again
E) Southern blots cannot test for the presence of the sickle cell allele

Question

Quizplus · Accepted Answer

The presence of two small bands for the Hbb? allele and one band for the Hbb allele indicates that the subject is heterozygous for the sickle cell allele. The small bands represent the sickle cell allele and the larger band represents the normal Hbb allele.

When Testing for the Presence of the Sickle Cell Anemia