When replicating the end of a chromosome,the lagging strand cannot copy the last ~10 nucleotides at the end of the chromosome.As a result,chromosomes contain telomere sequences at their ends,which are defined as:
A)special DNA sequences that do not require priming for replication.
B)noncoding,repetitive sequences that can be copied independent of the replisome.
C)noncoding,repetitive sequences that are not replicated during DNA replication.
D)protein-based structures at the ends of chromosomes that protect the chromosome end.
E)All of the answer options are correct.

Question

Quizplus · Accepted Answer

Telomere sequences are noncoding, repetitive sequences that can be copied independently of the replisome. They serve as a buffer against the loss of genetic information during DNA replication, as the lagging strand cannot copy the last ~10 nucleotides at the end of the chromosome. These repeated sequences protect the genetic information at the end of the chromosome from being degraded or lost during subsequent cell divisions.

When Replicating the End of a Chromosome,the Lagging Strand Cannot