The complexity of lagging strand replication is necessary because:
A)there is room for only a single DNA polymerase III enzyme in the replisome.
B)the helicase can only unwind double-helical DNA slowly.
C)as polymerization occurs only in the 5′ to 3′ direction,the lagging strand must be synthesized in consecutive small fragments.
D)the RNA primase works better on the leading strand DNA.
E)DNA polymerase I is more often associated with the lagging strand.

Question

Quizplus · Accepted Answer

The lagging strand must be synthesized in consecutive small fragments because polymerization occurs only in the 5′ to 3′ direction. This is necessary to ensure that the DNA synthesis occurs smoothly without introducing any errors or mismatches. The complexity of lagging strand replication is mainly due to this reason. The other options are not correct as they do not accurately describe the challenges associated with lagging strand replication.

The Complexity of Lagging Strand Replication Is Necessary Because