Topoisomerase and Helicase Have Distinct Functions That Include Which of the Following

Topoisomerase and helicase have distinct functions that include which of the following?

A) Topoisomerase is responsible for unwinding the double helix (separating strands) .
B) Helicase is responsible for unwinding the double helix (separating strands) .
C) Helicase relieves supercoiling that occurs in front of the replication fork.
D) The enzymes have nearly identical activities but are located at different sites during DNA replication.
E) These enzymes are nearly identical but have been given distinct names.