Before the completion of the human genome project,it was generally estimated that human DNA would contain up to 100,000 genes.We now know humans contain only around 25,000 individual genes within our genomes.This "gene count" is so surprising because: A)simple roundworms have over 10,000 genes,so humans should have many more. B)experimental analysis of mRNA diversity generated estimates of ~100,000 genes. C)humans have a large genome size (3.3 $\times$ 10⁹ base pairs). D)the diverse types of tissue in humans require many thousands of genes. E)All of the answer options are correct.

Question

Quizplus · Accepted Answer

The initial surprise at the human gene count being around 25,000, despite earlier estimates of up to 100,000, stems from several factors: the complexity and diversity of human biology compared to simpler organisms like roundworms, experimental analyses suggesting higher numbers, the large size of the human genome, and the diversity of human tissue types, all of which seemed to imply a need for a larger number of genes.

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