The Polymerase Chain Reaction Requires SsDNA Primers That

The polymerase chain reaction requires ssDNA primers that:

A) anneal to the same strand of template DNA,though at distant sites.
B) anneal to opposite strands of template DNA at distant sites,with their 3′ ends directed toward each other.
C) anneal to opposite strands of template DNA at distant sites,with their 5′ ends directed toward each other.
D) anneal to each other to prime DNA polymerization.
E) hybridize only to DNA within the open reading frame of a selected gene.