What type of library would be most valuable in the isolation of promoter sequences found in front of a gene's transcriptional start site?
A)genomic DNA library
B)cDNA library
C)miRNA library
D)mutant genomic DNA library
E)repetitive DNA library

Question

Quizplus · Accepted Answer

A genomic DNA library is the best choice for isolating promoter sequences found in front of a gene's transcriptional start site as it contains the complete set of DNA sequences from an organism, including promoter regions. Promoter sequences are located upstream of the transcriptional start site and can vary in length, making isolation from a cDNA library difficult. A mutant genomic DNA library would not be useful in this case as it would contain mutations in the DNA sequence, potentially affecting the promoter region. miRNA and repetitive DNA libraries are unrelated to the isolation of promoter sequences.

What Type of Library Would Be Most Valuable in the Isolation