In the course of estimating the degree of linkage of a marker and a quantitative trait of interest,researchers announced that they obtained a LOD score of 4.5.This finding indicates that:
A)there is a 4.5% chance that an individual with the marker will also show the trait of interest.
B)the marker is 4.5 map units away from the QTL controlling the trait of interest.
C)the marker is most likely not linked to the QTL controlling the trait of interest.
D)the odds that the marker is linked to the QTL controlling the trait of interest are 4.5:1.
E)the odds that the marker is linked to the QTL controlling the trait of interest are 4500:1.

Question

Quizplus · Accepted Answer

A LOD (Logarithm of the Odds) score of 4.5 indicates that the odds of linkage between the marker and the quantitative trait locus (QTL) are 10^4.5 to 1, which simplifies to 4500:1, suggesting strong evidence of linkage.

In the Course of Estimating the Degree of Linkage of a Marker