Which of the following reactions, if coupled to the reduction of -ketoglutarate, would give the most exergonic overall reaction? -ketoglutarate + CO2 + 2H+ + 2e- isocitrate (E ' = - 0.38 V)
A) ubiquinol ubiquinone + 2H+ + 2e- (E ' = - 0.04 V)
B) FADH2 FAD + 2H+ + 2e- (E ' = + 0.22 V)
C) NADH NAD+ + H+ + 2e- (E ' = + 0.32 V)
D) H2 2H+ + 2e- (E ' = + 0.42 V)
E) pyruvate + CoA acetyl CoA + CO2 + H+ + 2e- (E ' = + 0.48 V)
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