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Which of the Following Reactions, If Coupled to the Reduction α\alpha

Question 6

Multiple Choice

Which of the following reactions, if coupled to the reduction of α\alpha -ketoglutarate, would give the most exergonic overall reaction? α\alpha -ketoglutarate + CO2 + 2H+ + 2e- \rarr isocitrate (E \circ ' = - 0.38 V)


A) ubiquinol \rarr ubiquinone + 2H+ + 2e- (E \circ ' = - 0.04 V)
B) FADH2 \rarr FAD + 2H+ + 2e- (E \circ ' = + 0.22 V)
C) NADH \rarr NAD+ + H+ + 2e- (E \circ ' = + 0.32 V)
D) H2 \rarr 2H+ + 2e- (E \circ ' = + 0.42 V)
E) pyruvate + CoA \rarr acetyl CoA + CO2 + H+ + 2e- (E \circ ' = + 0.48 V)

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