Glu 35 of lysozyme is found in a nonpolar environment.Which of the following is true?
A)Its pK is lower than the usual value in this environment.
B)Its pK is higher than the usual value in this environment.
C)Its pK would not change in this environment.
D)Its pK would depend on the sample buffer.
E)None of the above is correct.

Question

Quizplus · Accepted Answer

In a nonpolar environment, the pK of an amino acid like Glu 35 would be higher than its usual value because the lack of polarity would make it more difficult for the amino acid to donate a proton, thus requiring a higher pH (or pK) to ionize compared to its behavior in a more polar or aqueous environment.

Glu 35 of Lysozyme Is Found in a Nonpolar Environment