Lysozyme requires _____ for effective catalysis.
(I)an Asp in a nonpolar environment
(II)a negatively charged Asp
(III)a Glu that functions as an acid catalyst
(IV)a Glu that is deprotonated
A)I,II,III,IV
B)I,III
C)II,III
D)II,IV
E)I,IV

Question

Quizplus · Accepted Answer

Lysozyme requires a Glu that functions as an acid catalyst and a negatively charged Asp for effective catalysis. Therefore, options I and IV are incorrect. Option II is correct because a negatively charged Asp is required for the formation of the enzyme-substrate complex. Option III is also correct because a Glu functions as an acid catalyst during the catalytic reaction. Thus, the best choice is C.

Lysozyme Requires _____ for Effective Catalysis