Which of the following represents a point of regulation for the citric acid cycle?
(I)pyruvate dehydrogenase complex
(II)aconitase
(III)isocitrate dehydrogenase
(IV)fumarase
A)I,II,III,IV
B)I,II,IV
C)II,III
D)I,III
E)I,IV

Question

Quizplus · Accepted Answer

The citric acid cycle is regulated at several key enzymatic steps to efficiently manage energy production based on cellular needs. The pyruvate dehydrogenase complex, which converts pyruvate into acetyl-CoA (a substrate for the citric acid cycle), and isocitrate dehydrogenase, an enzyme within the cycle that catalyzes the oxidative decarboxylation of isocitrate to alpha-ketoglutarate, are both points of regulation. Aconitase and fumarase, on the other hand, are involved in the cycle but are not major regulatory points.

Which of the Following Represents a Point of Regulation for the Citric