How does the preinitiation complex begin to form at a TATA box-containing promoter?
A)RNAP binds to the sigma factor.
B)RNAP binds to the initiator (Inr)element.
C)TATA-binding protein binds to the TATA box.
D)RNAP binds to the Rho factor.
E)none of the above.

Question

Quizplus · Accepted Answer

The preinitiation complex begins to form at a TATA box-containing promoter when the TATA-binding protein (TBP) binds to the TATA box, which is typically located approximately 25 nucleotides upstream of the transcription start site. TBP binding leads to the recruitment of other transcription factors and RNAP, ultimately resulting in the formation of the preinitiation complex and the initiation of transcription.

How Does the Preinitiation Complex Begin to Form at a TATA