The phosphorylation of the CTD of RNA polymerase II is important for which phase of transcription?
A)initial binding of the promoter
B)conversion from the pre-initiation (closed)complex to the initiation (open)complex
C)progression from initiation to elongation
D)termination of transcription
E)none of the above

Question

Quizplus · Accepted Answer

The phosphorylation of the CTD of RNA polymerase II is important for progression from initiation to elongation in transcription. Phosphorylation of the CTD allows for the release of the transcription factors from the promoter region and allows for the recruitment of elongation factors to promote the movement of RNA polymerase II along the DNA template to synthesize the RNA transcript.

The Phosphorylation of the CTD of RNA Polymerase II Is