Which of the following factors may stimulate pulmonary vascular spasm and cause persistent pulmonary hypertension of the newborn?
1) Hypoxemia
2) Hypoglycemia
3) Hypotension
4) Pain

Question

Quizplus · Accepted Answer

Persistent pulmonary hypertension of the newborn (PPHN) can be stimulated by various factors that lead to hypoxic pulmonary vasoconstriction. These factors include hypoxemia, which directly causes pulmonary vessels to constrict in an attempt to divert blood away from poorly oxygenated areas; hypoglycemia, which can indirectly contribute to the condition by affecting overall cellular function and stress responses; hypotension, which can exacerbate hypoxia and contribute to the stress response; and pain, which can cause a stress response leading to increased pulmonary vascular resistance. All these factors can contribute to the pathophysiology of PPHN by increasing pulmonary vascular resistance and exacerbating the condition.

Which of the Following Factors May Stimulate Pulmonary Vascular Spasm