Consider the following interaction between a protein and its ligand: [P] + [L] [PL].Which equation describes the dissociation constant of this interaction?
A) [PL] / [P][L]
B) [P][L] / [PL]
C) [PL] / [P]
D) [PL][P] / [L]

Question

Consider the following interaction between a protein and its ligand: [P] + [L]  [PL].Which equation describes the dissociation constant of this interaction?
A) [PL] / [P][L] 
B) [P][L] / [PL] 
C) [PL] / [P] 
D) [PL][P] / [L]

Quizplus · Accepted Answer

The dissociation constant, KD, for the interaction between P and L is defined as [P][L]/[PL], so the correct equation would be B.

Consider the Following Interaction Between a Protein and Its Ligand