If an enzyme carries out acid-base catalysis,which of the following amino acids could act as general acid?
A) phenylalanine
B) glycine
C) histidine
D) alanine

Question

Quizplus · Accepted Answer

Histidine has a side chain with a pKa close to neutral pH, making it well-suited to act as a general acid in acid-base catalysis. Phenylalanine, glycine, and alanine do not have ionizable side chains and are not capable of acting as general acids in this context.

If an Enzyme Carries Out Acid-Base Catalysis,which of the Following