Place the following steps of the apoptotic pathway in their proper order.
A.CASP3 cleavage of cellular proteins
B.Cleavage of procaspase 8
C.Cleavage of procaspase 3
D.Assembly of DD and DED protein complexes
A) D, C, B, A
B) B C, A, D
C) D, B, C, A
D) D, C, A, B

Question

Place the following steps of the apoptotic pathway in their proper order. 
A.CASP3 cleavage of cellular proteins
B.Cleavage of procaspase 8
C.Cleavage of procaspase 3
D.Assembly of DD and DED protein complexes
A) D, C, B, A
B) B C, A, D
C) D, B, C, A
D) D, C, A, B

Quizplus · Accepted Answer

The apoptotic pathway begins with the assembly of DD and DED protein complexes (D), followed by the activation of procaspase 8 through cleavage (B), which then cleaves and activates procaspase 3 (C). Finally, caspase 3 cleaves cellular proteins (A). Therefore, the correct order is D, B, C, A, which is only seen in choice C.

Place the Following Steps of the Apoptotic Pathway in Their