Why is the of the condensation of oxaloacetate and acetyl-CoA highly favorable? A) The addition of inorganic phosphate provides energy, resulting in the highly favorable nature of this reaction. B) Allosteric regulations of the reaction cause a release of energy, making the reaction thermodynamically favorable. C) The iron-sulfur cluster in the enzyme reduces the activation energy of the reaction, resulting in the favorable D) The hydrolysis of the thioester bond in citryl-CoA results in the highly exergonic reaction.

Question

Quizplus · Accepted Answer

The hydrolysis of the thioester bond in citryl-CoA releases a large amount of energy, making the reaction highly exergonic and thermodynamically favorable. This reaction is a key step in the Krebs cycle, where citrate is oxidized to generate ATP, and the release of energy from the hydrolysis of the thioester bond drives the reaction forward.

Why Is the of the Condensation of Oxaloacetate