The DNA alkylation of guanine is possible because the __________ of guanine is __________ and reacts rapidly with __________ alkylating agents.
A) N-7; nucleophilic; electrophilic
B) N-5; nucleophilic; electrophilic
C) N-7; electrophilic; nucleophilic
D) N-5; electrophilic; nucleophilic

Question

Quizplus · Accepted Answer

The N-7 position of guanine is nucleophilic, meaning it has a lone pair of electrons that can react with electrophilic alkylating agents, which seek electrons.

The DNA Alkylation of Guanine Is Possible Because the __________