A 58-year-old woman, who had a total abdominal hysterectomy at the age of 45, is diagnosed with atrophic vaginitis.Which of the following is the most appropriate treatment?

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Quizplus · Accepted Answer

Atrophic vaginitis refers to inflammation of the vaginal mucosa due to decreased estrogen levels, which typically occurs after menopause or in women who have had a hysterectomy. The most appropriate treatment is topical estrogen therapy, which helps to restore vaginal lubrication, elasticity, and pH balance. Systemic estrogen therapy, such as oral conjugated estrogen or the combination of conjugated estrogen and medroxyprogesterone, may also be effective but carries a higher risk of side effects. Vaginal estrogens, such as the estradiol vaginal ring, have a lower risk of side effects as the dose is localized to the vaginal tissue. Medroxyprogesterone is a progestin, which is often prescribed in addition to estrogen in women who have not had a hysterectomy to reduce the risk of endometrial cancer. However, in a woman who has had a total hysterectomy, progestins are not necessary. Therefore, the most appropriate treatment option is estradiol vaginal ring.

A 58-Year-Old Woman, Who Had a Total Abdominal Hysterectomy at the Age