A CBC,differential,and flow cytometry were performed on a patient with the following results (normal values): WBC = 8.0 th/uL (5.0-10.0 th/uL),diff = 90% lymphs (20-40%),CD3 = 5% (60-80%),CD5 = 95% (60-80%),CD19 = 95% (5-20%),CD10 = 0% (0%),surface Ig = pos (positive),and cytoplasmic Ig = neg (negative).What disease does this patient have?

Question

Quizplus · Accepted Answer

The patient has an elevated WBC count and a differential showing 90% lymphocytes. The flow cytometry results show a B-cell phenotype with CD19 and surface Ig positivity, as well as CD5, which is associated with B-cell chronic lymphocytic leukemia (B-CLL). The absence of CD10 excludes the possibility of B-cell acute lymphocytic leukemia (B-ALL). The T-cell markers (CD3) are decreased, making T-cell lymphocytic leukemia an unlikely diagnosis. Lastly, there is no evidence of HIV/AIDS based on the given results.

A CBC,differential,and Flow Cytometry Were Performed on a Patient with the Following