What is the interpretation of the following patient results? (normal values)WBC = 7.0 th/uL (5.0-10.0 th/uL),with 89% blasts; CD3 = 10% (60-80%); CD5 = 9% (60-80%); CD10 = 89% (

Question

What is the interpretation of the following patient results? (normal values)WBC = 7.0 th/uL (5.0-10.0 th/uL),with 89% blasts; CD3 = 10% (60-80%); CD5 = 9% (60-80%); CD10 = 89% (< 1%); CD4 = 6% (30-65%); CD20 = 0% (5-20%); CD34 = 94% (< 1%); CD8 = 3% (10-40%); kappa = 0% (3-15%); lambda = 0% (2-10%); CD19 = 90% (5-20%).

Quizplus · Accepted Answer

The patient's WBC count is within the normal range, but the high percentage of blasts (immature white blood cells) indicates a pathology. The CD markers indicate a predominance of CD10 and CD19, which are usually found on B-cells. The CD34 marker is also significantly elevated, which is a common marker for acute leukemia. The absence of CD20, which is expressed on nearly all mature B-cells and most B-cell malignancies, further supports a diagnosis of B-cell acute leukemia.

What Is the Interpretation of the Following Patient Results? (Normal