When IgM on the surface of an immature B cell binds to a self-antigen,which of the following processes can occur?

Question

Quizplus · Accepted Answer

When a self-antigen binds to IgM on the surface of an immature B cell, it can trigger apoptosis (cell death) to eliminate the autoreactive B cell. This is a mechanism of tolerance to prevent the development of autoimmune diseases. Class switch and affinity maturation occur during the later stages of B cell maturation and require activation by foreign antigens. Differentiation can also occur later in response to specific stimuli.

When IgM on the Surface of an Immature B Cell