B cells that respond against self-antigens will undergo:

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B cells that respond against self-antigens will undergo all of the following: receptor editing, anergy, and apoptosis. Receptor editing is a process where the B cell receptor is edited to decrease self-reactivity. If this process fails, the B cell becomes anergic, which means it is unable to respond to further stimulation. If the anergic B cell continues to receive stimulation, it undergoes apoptosis. Therefore, all three processes occur in sequence to prevent the development of autoimmune diseases.

B Cells That Respond Against Self-Antigens Will Undergo