If donor cells were coated with antibody resulting in a positive DAT, what phase of the major crossmatch would generally react?

Question

Quizplus · Accepted Answer

The antibody coating the donor cells would be detected in the AHG phase of the major crossmatch, as this phase is designed to detect IgG antibodies. The IS and 37 phases do not involve the detection of antibodies, but rather the detection of incompatible antigens on the donor cells. Therefore, the correct choice is C.

If Donor Cells Were Coated with Antibody Resulting in a Positive