Given the following results, what is the probable cause of a positive reaction in the major crossmatch? IS = 0 37?0°C = 0 AHG = 2+ CC = ND Auto-control was negative

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The positive reaction in the major crossmatch with 2+ AHG indicates the presence of alloantibody in the patient serum that is reacting with an antigen on the donor cells. The negative auto-control rules out the possibility of non-specific agglutination. Incorrect ABO grouping of the patient or donor would result in an immediate spin crossmatch incompatibility, which is not evident in these results. Autoantibody in patient serum reacting with donor cells would also be reflected in a positive auto-control. Rouleaux is a phenomenon of RBC clumping due to the presence of plasma proteins and does not cause agglutination in the absence of an immunological reaction.

Given the Following Results, What Is the Probable Cause of a Positive