Mixing patient serum and donor red blood cells together and observing for direct cell lysis or agglutination is known as:

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The major crossmatch involves mixing the patient serum with donor red blood cells to determine if there is any compatibility or incompatibility between the two. Direct cell lysis or agglutination indicates incompatibility and potential transfusion reaction. The Donath-Landsteiner test is used to diagnose paroxysmal cold hemoglobinuria, the minor crossmatch involves mixing the donor serum with patient red blood cells, and the autohemolysis test involves observing the patient's own red blood cells for lysis.

Mixing Patient Serum and Donor Red Blood Cells Together and Observing