Recipient serum that reacted with one out of five donor units in the AHG phase and where the antibody screen was negative is probably due to:

Question

Quizplus · Accepted Answer

The fact that the recipient serum reacted with only one out of five donor units in the AHG phase suggests the presence of a low-frequency alloantibody. Additionally, the negative antibody screen rules out any common antibodies, while the ABO mismatch is not relevant to this scenario. There is no evidence of coating of recipient cells with alloantibodies either. Therefore, option B is the best choice.

Recipient Serum That Reacted with One Out of Five Donor