Question 1

What is the most critical step in blood transfusion?

Accepted Answer

Checking patient identification and compatibility of donor unit is the most critical step in blood transfusion as it ensures that the patient receives compatible blood and reduces the risk of adverse reactions. Phenotyping units, following quality control procedures, and monitoring temperature control are all important steps, but their significance is secondary to patient identification and compatibility checks.

Question 2

An ABO antibody will cause a more severe hemolytic transfusion reaction in a patient who has received mismatched blood than an alloantibody will.

Accepted Answer

ABO antibodies are naturally occurring antibodies in individuals who lack the corresponding ABO antigens on their own red blood cells. These antibodies are extremely potent and can cause a severe hemolytic transfusion reaction if the patient receives blood from a donor with a mismatched ABO type. In contrast, alloantibodies are antibodies formed in response to an individual receiving multiple transfusions or from previous pregnancies. While alloantibodies can also cause a transfusion reaction, they are generally less potent than ABO antibodies.

Question 3

In an intrauterine transfusion, whose serum is used for compatibility testing?

Accepted Answer

The mother's serum is used for compatibility testing in an intrauterine transfusion as she is the source of the fetal blood antigens.

Quiz 10: Pre-Transfusion Testing

What is the most critical step in blood transfusion?

An ABO antibody will cause a more severe hemolytic transfusion reaction in a patient who has received mismatched blood than an alloantibody will.

In an intrauterine transfusion, whose serum is used for compatibility testing?