If a patient's APTT is normal, but their PT is prolonged, this could be due to:

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A normal Activated Partial Thromboplastin Time (APTT) with a prolonged Prothrombin Time (PT) suggests a defect in the extrinsic or common coagulation pathway. Liver disease, Factor VII deficiency, Vitamin K deficiency, and anti-vitamin K therapy can all affect the production or function of clotting factors involved in the extrinsic and common pathways, particularly factors II, VII, IX, and X, with Factor VII being directly tested by PT.

If a Patient's APTT Is Normal, but Their PT Is