The treatment of choice for chronic ITP after failure to maintain an adequate response to steroid therapy is _________.

Question

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When patients fail to maintain an adequate response to steroid therapy, splenectomy is the treatment of choice for chronic ITP. It provides a sustained response/remission in about 60-80% of the patients. Gamma globulin and plasma exchange can be used as temporary measures to increase platelet count, but they are not curative options. Immunosuppressive drugs can be effective in some cases, but there is a risk of significant side effects and their long-term use is not recommended.

The Treatment of Choice for Chronic ITP After Failure to Maintain