Which laboratory test(s) should be ordered to evaluate a patient suspected of having plasma cell disorder?

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All of the above tests are relevant when evaluating a patient for a plasma cell disorder. Serum protein electrophoresis (SPEP) can detect monoclonal gammopathy, which is common in plasma cell disorders. Elevated calcium levels can occur due to bone breakdown from plasma cell proliferation. Blood urea nitrogen (BUN) can be elevated due to kidney damage, which is a complication of plasma cell disorders. Erythrocyte sedimentation rate (ESR) can be elevated due to the inflammatory process associated with these disorders.

Which Laboratory Test(s) Should Be Ordered to Evaluate a Patient