This acute leukemia contains primarily abnormal promyelocytes with heavy granulation, and the presence of Auer rods is abundant. The cells react near 100% with Sudan black and peroxidase; however, the reaction is negative for non-specific esterase. Disseminating intravascular coagulation (DIC) is frequently associated with this disorder. What is the FAB classification?

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The heavy granulation, presence of Auer rods, and high reactivity with Sudan black and peroxidase are indicative of acute promyelocytic leukemia (APL), which is classified as M3 according to the FAB classification. DIC is a common complication of APL.

This Acute Leukemia Contains Primarily Abnormal Promyelocytes with Heavy Granulation