Which of the following therapies represents the "mainstay" of treatment for painful crises to correct fluid and electrolyte deficits in patients with sickle cell anemia?

Question

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Hydration, specifically administration of fluid volume, is the mainstay of treatment for painful crises in patients with sickle cell anemia to correct fluid and electrolyte deficits caused by the disease. Aspirin may be used for pain relief, antibiotics for infections, transfusion therapy for severe cases, and plasmapheresis for certain complications, but none of these are the mainstay of treatment for painful crises in sickle cell anemia.

Which of the Following Therapies Represents the "Mainstay" of Treatment