Which process listed below is commonly responsible for the symptoms of the hand-foot syndrome observed in sickle cell anemia?

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The hand-foot syndrome (also known as dactylitis) is a common feature of sickle cell anemia, and it is caused by infarction of small vessels in the hands and feet. This leads to inflammation, pain, and swelling in these areas. Infarction is a hallmark of sickle cell disease, and it is caused by the polymerization of sickle hemoglobin, which leads to the occlusion of blood vessels.

Which Process Listed Below Is Commonly Responsible for the Symptoms