Which of the Following Is Characteristic of PK Deficiency

Which of the following is characteristic of PK deficiency?

A) The severity of the hemolytic anemia varies widely
B) Varying degrees of polychromasia and poikilocytosis may be found on the peripheral smear and nucleated red cells may be seen
C) Clinical manifestations commonly found include splenomegaly and cholelithiasis
D) Onset may be during infancy or early childhood and mild cases may not be detected until adulthood
E) All of the above