Which condition will lead to iron-deficiency anemia masking the diagnosis of PNH?

Question

Quizplus · Accepted Answer

Iron-deficiency anemia can cause the absence of hemosiderin in urine, which is the hallmark of PNH. Therefore, in the absence of hemosiderinuria, PNH may not be diagnosed. Hemoglobinuria (A) is a symptom of PNH, so it would not mask the diagnosis. Hemoglobinemia (C) is the presence of free hemoglobin in the blood, which is a symptom of PNH, so it would not mask the diagnosis. Hemochromatosis (D) is a genetic disorder that causes excess iron absorption and could potentially increase the risk of having PNH, but it would not mask the diagnosis. Therefore, the correct answer is B.

Which Condition Will Lead to Iron-Deficiency Anemia Masking the Diagnosis