In differentiating PNH red cells from normal red cells in the sugar water test, PNH red cells will be _________________.

Question

Quizplus · Accepted Answer

PNH (Paroxysmal Nocturnal Hemoglobinuria) red cells are more susceptible to complement-mediated lysis due to the absence of GPI-anchored proteins that normally protect the cell membrane. In the sugar water test, which is a hypotonic solution, PNH red cells are more likely to lyse compared to normal red cells.

In Differentiating PNH Red Cells from Normal Red Cells in the Sugar