Although effective,electroconvulsive therapy for depression:

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Electroconvulsive therapy (ECT) has been shown to be effective in treating depression. However, once the treatments are discontinued, there is a high risk of relapse. This is why ECT is usually used in combination with other treatments such as medication and therapy to help prevent relapse. ECT does not invariably result in permanent brain damage, and it is not generally considered unethical by the scientific community when used appropriately. While there is some evidence to suggest that unilateral ECT (applied to only one hemisphere) may be more effective and have fewer side effects than bilateral ECT (applied to both hemispheres), both approaches are used in practice.

Although Effective,electroconvulsive Therapy for Depression