The hydrolysis of phosphatidyl inositol-bisphosphate (PIP₂) results in A) inositol trisphosphate and diacylglycerol. B) inositol trisphosphate and cyclic AMP. C) one second-messenger molecule. D) G protein activation. E) shutdown of a signal transduction pathway.

Question

Quizplus · Accepted Answer

The hydrolysis of phosphatidyl inositol-bisphosphate (PIP₂) leads to the production of inositol trisphosphate and diacylglycerol, two second-messenger molecules that play important roles in activating various signaling pathways. Therefore, choice A is the best answer. Choice B is incorrect because cyclic AMP is not produced from PIP₂ hydrolysis. Choice C is incorrect because multiple second-messenger molecules are produced. Choice D may occur downstream in the signaling pathway, but it is not a direct result of PIP₂ hydrolysis. Choice E is incorrect because the hydrolysis of PIP₂ actually activates a signal transduction pathway.

The Hydrolysis of Phosphatidyl Inositol-Bisphosphate (PIP2) Results in

The Hydrolysis of Phosphatidyl Inositol-Bisphosphate (PIP₂) Results in